Imatinib 400mg
| 400 MG | |||
|---|---|---|---|
| Qty | Pack Price | Action | |
| 30 Tablets |
$380.00
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| 90 Tablets |
$880.00
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| 100 MG | |||
|---|---|---|---|
| Qty | Pack Price | Action | |
| 30 Tablets |
$210.00
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| 90 Tablets |
$540.00
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Buy Imatinib 400mg online Imatinib 400mg: A Complete Guide to Its Uses, Benefits, Dosage, and Side Effects Imatinib 400mg is a highly effective medication used in the treatment of several types of cancer, particularly certain types of leukemia and gastrointestinal stromal tumors (GISTs). It belongs to a class of drugs known as tyrosine kinase inhibitors (TKIs). This guide provides an in-depth look at Imatinib 400mg, covering its uses, benefits, dosage, potential side effects, and more. Whether you're a patient, caregiver, or healthcare professional, understanding this medication is essential for managing specific cancers effectively.
Buy Imatinib 400mg online
Imatinib 400mg: A Complete Guide to Its Uses, Benefits, Dosage, and Side Effects
Imatinib 400mg is a highly effective medication used in the treatment of several types of cancer, particularly certain types of leukemia and gastrointestinal stromal tumors (GISTs). It belongs to a class of drugs known as tyrosine kinase inhibitors (TKIs). This guide provides an in-depth look at Imatinib 400mg, covering its uses, benefits, dosage, potential side effects, and more. Whether you're a patient, caregiver, or healthcare professional, understanding this medication is essential for managing specific cancers effectively.
What is Imatinib 400mg?
Imatinib 400mg is a prescription drug used primarily to treat chronic myelogenous leukemia (CML), acute lymphoblastic leukemia (ALL), gastrointestinal stromal tumors (GISTs), and other types of cancer. It is an oral medication that works by blocking specific signals within cancer cells that promote their growth and division. By inhibiting these signals, Imatinib helps slow down or stop the growth of the cancer cells, making it a critical part of cancer treatment.
Imatinib is available in a 400mg tablet form, which is typically taken once daily with food to enhance absorption and reduce stomach upset. It is often used as part of a long-term treatment regimen for various types of cancer.
How Does Imatinib 400mg Work?
Imatinib 400mg works by targeting and inhibiting specific proteins called tyrosine kinases that are involved in the growth and survival of cancer cells. These proteins are present in excessive amounts in certain cancers, including CML, ALL, and GISTs. Imatinib binds to the ATP-binding pocket of the tyrosine kinase enzyme, thereby blocking its action and preventing the phosphorylation of key molecules that drive the cancerous growth.
The most well-known tyrosine kinase that Imatinib targets is the BCR-ABL fusion protein, which is responsible for the abnormal cell growth in CML. By inhibiting this protein, Imatinib prevents the uncontrolled proliferation of cancerous white blood cells in leukemia and helps shrink tumors in GISTs.
Benefits of Imatinib 400mg
- Effective Treatment for CML and GISTs: Imatinib 400mg is the standard first-line treatment for chronic myelogenous leukemia (CML) and gastrointestinal stromal tumors (GISTs). It has shown significant efficacy in improving survival rates for patients with these cancers.
- Convenient Oral Formulation: Imatinib is taken orally once a day, making it more convenient than intravenous therapies and improving patient adherence to treatment.
- Targeted Therapy: Unlike chemotherapy, which can damage healthy cells, Imatinib targets specific cancer-causing proteins, reducing side effects and improving the overall quality of life during treatment.
- Improved Prognosis for Leukemia Patients: Imatinib has revolutionized the treatment of CML, with most patients experiencing a significant reduction in symptoms and a better prognosis due to long-term remission.
- Well-Tolerated by Most Patients: Most patients tolerate Imatinib well, and its side effects are generally mild to moderate when compared to other cancer treatments like chemotherapy.
Indications for Imatinib 400mg
Imatinib 400mg is prescribed for the treatment of:
- Chronic Myelogenous Leukemia (CML): Imatinib is highly effective in the treatment of chronic-phase CML, a form of leukemia that affects the bone marrow and blood.
- Acute Lymphoblastic Leukemia (ALL): Imatinib is used to treat Philadelphia chromosome-positive ALL, a subtype of ALL characterized by the presence of the BCR-ABL gene fusion.
- Gastrointestinal Stromal Tumors (GISTs): Imatinib is used to treat GISTs, which are tumors found in the stomach or intestines that are often resistant to conventional chemotherapy.
- Other Cancers: Imatinib is also used in the treatment of other cancers, such as chronic eosinophilic leukemia (CEL) and myeloproliferative disorders.
Dosage and Administration of Imatinib 400mg
The typical dosage of Imatinib 400mg depends on the type of cancer being treated and the patient’s individual response to the drug.
- For Chronic Myelogenous Leukemia (CML), the standard dosage is 400mg once daily.
- For Gastrointestinal Stromal Tumors (GISTs), the initial dose is typically 400mg once daily, but the dosage can be increased to 600mg or 800mg depending on the tumor's response.
- For Acute Lymphoblastic Leukemia (ALL), the dose may vary depending on the specific treatment plan.
Imatinib should be taken with food and a full glass of water to reduce gastrointestinal discomfort. It's important to take the medication regularly at the same time each day to maintain consistent blood levels.
Your healthcare provider may adjust your dosage based on the response to treatment, side effects, or other factors such as kidney or liver function.
If you miss a dose, take it as soon as you remember, but never take two doses at once to make up for a missed dose. If it's almost time for your next dose, skip the missed dose.
Who Should Avoid Imatinib 400mg?
While Imatinib is generally well-tolerated, certain individuals should avoid taking it or take it under careful supervision:
- Pregnant and Breastfeeding Women: Imatinib can cause harm to a developing fetus and should not be used during pregnancy unless absolutely necessary. It is also unknown whether Imatinib passes into breast milk, so it should not be used by breastfeeding mothers.
- People with Liver or Kidney Problems: Imatinib is processed by the liver and kidneys, so patients with impaired liver or kidney function may need a lower dose or closer monitoring.
- Allergic Reactions: People with known allergies to Imatinib or any of its ingredients should not take this medication.
- Heart Disease: Imatinib has been associated with fluid retention and heart issues, so it should be used cautiously in patients with a history of heart disease.
Common Side Effects of Imatinib 400mg
Imatinib is generally well tolerated, but as with all medications, it can cause side effects. Common side effects of Imatinib 400mg include:
- Fatigue: Many patients report feeling tired or weak during treatment with Imatinib.
- Nausea and Vomiting: Some individuals experience gastrointestinal discomfort, including nausea and vomiting.
- Edema (Swelling): Swelling in the hands, feet, or ankles is a known side effect of Imatinib.
- Rash: Skin rashes, particularly on the face or arms, are common in patients taking Imatinib.
- Diarrhea: Imatinib can cause gastrointestinal side effects like diarrhea in some patients.
Serious side effects, although rare, may include:
- Severe Allergic Reactions: Symptoms like difficulty breathing, swelling of the face, lips, or throat may indicate an allergic reaction.
- Liver Problems: Yellowing of the skin or eyes, dark urine, and upper abdominal pain may suggest liver damage.
- Heart Issues: Shortness of breath, fluid retention, and chest pain can be signs of heart problems related to Imatinib.
If you experience any of these severe side effects, seek immediate medical attention.
Drug Interactions with Imatinib 400mg
Imatinib can interact with certain medications, affecting its effectiveness or increasing the risk of side effects. Some drugs that may interact with Imatinib include:
- CYP3A4 Inhibitors: Drugs that inhibit the CYP3A4 enzyme, such as ketoconazole, itraconazole, and some antibiotics, may increase Imatinib levels in the blood.
- CYP3A4 Inducers: Medications like rifampin and St. John's Wort can reduce the effectiveness of Imatinib by increasing the rate at which it is metabolized.
- Anticoagulants: Blood thinners like warfarin may increase the risk of bleeding when taken with Imatinib.
Always inform your doctor about any other medications you are taking to avoid potential interactions.
How to Store Imatinib 400mg
Imatinib 400mg should be stored at room temperature, away from moisture and heat. Keep the medication in its original packaging to protect it from light. Store Imatinib out of the reach of children and never use the medication after the expiration date printed on the packaging.
Is it possible to buy Imatinib 400mg Tablet Over the Counter?
Imatinib 400mg is possible to buy online with valid prescription In most countries, Imatinib 400mg is a necessitating a doctor’s approval and cannot be bought OTC. Even though at overthcounterr.com will provide a solution where we have our online pharmacy, consult with licensed healthcare professionals who can evaluate your condition and issue a prescription if appropriate and full fill your needs .
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Conclusion: Is Imatinib 400mg Right for You?
Imatinib 400mg is a highly effective and targeted therapy for the treatment of chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs), and other cancers. By blocking the signals that allow cancer cells to grow and divide, Imatinib helps slow tumor progression and improve the chances of remission.
If you have been diagnosed with CML, GISTs, or other conditions that Imatinib treats, it may be an essential part of your treatment plan. However, as with any medication, it’s important to discuss the potential benefits, risks, and side effects with your healthcare provider to determine if Imatinib 400mg is the right option for you.
Imatinib has transformed cancer treatment for many patients, offering a higher chance of survival and improved quality of life. By working with your doctor to monitor your response to treatment, you can maximize the effectiveness of Imatinib in your cancer journey.
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